The Substance Movie Poster

The Substance

User rating: 3.31 25 Reviews | Write a Review

In Theaters: September 20, 2024

On DVD/Blu-ray: January 21, 2025

R | Drama, Horror | 2h 20m

The Substance

Elisabeth Sparkle (Demi Moore), a former A-lister past her prime, is suddenly fired from her fitness TV show by repellent studio head Harvey (Dennis Quaid).

She is then drawn to the opportunity presented by a mysterious new drug: THE SUBSTANCE. All it takes is one injection and she is reborn – temporarily – as the gorgeous, twenty-something Sue (Margaret Qualley).

The only rule? Time needs to be split: exactly one week in one body, then one week in the other. No exceptions. A perfect balance. What could go wrong?

Cast: Demi Moore, Margaret Qualley, Dennis Quaid
Director: Coralie Fargeat
Studio: MUBI
Producer(s): Tim Bevan, Eric Fellner, Coralie Fargeat
Writer(s): Coralie Fargeat
Official Site: trythesubstance.com