Cats & Dogs

In this world, unbeknownst to man, there is a war brewing between cats and dogs. The cats plan to destroy a new vaccine, that if developed, would destroy all human allergies to dogs. A young pup (Maguire) must guard the vaccine with the help of a wise old dog (Sarandon), a large friendly dog (Duncan) and a small dog (Pantoliano) who is the electronics expert.